Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868134 | 0.85 | CA1 (0.40) | NPC1RAB9APOLBHPGDHSD17B10 | |
| SCHEMBL10449414 | 0.84 | NPC1 (0.41) | NPC1RAB9AHPGDHSD17B10TSHR | |
| SCHEMBL28383039 | 0.84 | NPC1 (0.51) | NPC1RAB9APOLBLMNAHPGD | |
| SCHEMBL29351738 | 0.80 | NPC1 (0.45) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL18928208 | 0.80 | KMT2A (0.53) | NPC1RAB9APOLBLMNAHPGD | |
| SCHEMBL226646 | 0.80 | NPC1 (0.45) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL5166388 | 0.80 | ALDH1A1 (0.47) | NPC1RAB9APOLBLMNAHPGD | |
| SCHEMBL28601258 | 0.79 | KDM4E (0.39) | NPC1RAB9APOLBLMNAHPGD | |
| SCHEMBL31309385 | 0.78 | NPC1 (0.59) | NPC1RAB9APOLBLMNAHPGD | |
| SCHEMBL2797053 | 0.78 | NPC1 (0.59) | NPC1RAB9APOLBLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071995-A | Excellent ultraviolet absorbability for polyesters and polyamides; high thermal stability | KURARAY CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0363839-A1 | 2-hydroxyphenylbenzotriazol compounds and the use thereof | KURARAY CO., LTD. (JP) | 1990-04-18 | — | — | EP | disclosed |