Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 4/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19473311 | 0.90 | ALDH1A1 (0.41) | ALDH1A1AAK1PPARGPPARAATM | |
| SCHEMBL18925550 | 0.90 | ALDH1A1 (0.41) | ALDH1A1AAK1PPARGPPARAATM | |
| SCHEMBL18918272 | 0.90 | ALDH1A1 (0.41) | ALDH1A1AAK1PPARGPPARAATM | |
| SCHEMBL18928769 | 0.86 | AAK1 (0.38) | AAK1ATMMMEMMEL1ACE | |
| SCHEMBL28509153 | 0.85 | ALDH1A1 (0.42) | ALDH1A1AAK1PPARGPPARAATM | |
| SCHEMBL28337609 | 0.84 | ALDH1A1 (0.42) | ALDH1A1AAK1PPARGPPARAATM | |
| SCHEMBL28337611 | 0.84 | ALDH1A1 (0.42) | ALDH1A1AAK1PPARGPPARAATM | |
| SCHEMBL28070782 | 0.84 | ATM (0.39) | ALDH1A1PPARGPPARAATMMME | |
| SCHEMBL28070779 | 0.84 | ATM (0.39) | ALDH1A1PPARGPPARAATMMME | |
| SCHEMBL28337627 | 0.82 | ATM (0.42) | ALDH1A1PPARGPPARAATMMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3210627-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | Hangzhou Dac Biotech Co., Ltd (CN) | 2017-08-30 | — | — | EP | disclosed |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | ALDH1A1 3672/4885AAK1 4026/4885PPARG 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.