Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420515 | 0.82 | LMNA (0.35) | LMNAALDH1A1TSHRTP53EGLN1 | |
| SCHEMBL10595982 | 0.82 | LMNA (0.35) | LMNATSHRTP53EGLN1EGLN3 | |
| SCHEMBL4416494 | 0.81 | — | — | |
| SCHEMBL27513944 | 0.78 | ALDH1A1 (0.38) | LMNAALDH1A1 | |
| SCHEMBL11250533 | 0.76 | ZDHHC20 (0.40) | ALDH1A1TSHR | |
| SCHEMBL4087560 | 0.76 | ALDH1A1 (0.37) | LMNAALDH1A1 | |
| SCHEMBL23504923 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL327366 | 0.73 | TSHR (0.38) | LMNAALDH1A1TSHRTP53EGLN1 | |
| SCHEMBL17156319 | 0.73 | TSHR (0.38) | LMNAALDH1A1TSHRTP53EGLN1 | |
| SCHEMBL8811631 | 0.70 | LMNA (0.39) | LMNAALDH1A1TSHRTP53EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026051-A1 | CATIONIC CYCLIC AMINE AND AMPHIPATHIC TRANSFECTION REAGENTS | MIRUS BIO LLC | 2024-01-25 | — | — | US | disclosed |
| US-11739174-B2 | Cationic cyclic amine and amphipathic transfection reagents | MIRUS BIO LLC (US) | 2023-08-29 | — | — | US | disclosed |
| US-10619162-B1 | Cationic cyclic amine and amphipathic transfection reagents | MIRUS BIO LLC (US) | 2020-04-14 | — | — | US | disclosed |
| US-9677077-B1 | Cationic acrylamide copolymer transfection reagents | MIRUS BIO LLC (US) | 2017-06-13 | — | — | US | disclosed |
| CN-1602835-B | Aerosol cosmetic composition | KAO CORP | 2013-01-02 | — | — | CN | disclosed |
| CN-102292067-A | Hair cosmetic composition | — | 2011-12-21 | — | — | CN | disclosed |
| CN-1602835-A | Aerosol cosmetic composition | KAO CORP (JP) | 2005-04-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10619162-B1 | Cationic cyclic amine and amphipathic transfection reagents | SLC7A1, PARN, PARG | LMNA 333/4885ALDH1A1 4841/4885TSHR 1244/4885 |
| US-20240026051-A1 | CATIONIC CYCLIC AMINE AND AMPHIPATHIC TRANSFECTION REAGENTS | SLC7A1, PARN, PARG | LMNA 333/4885ALDH1A1 4841/4885TSHR 1244/4885 |
| US-11739174-B2 | Cationic cyclic amine and amphipathic transfection reagents | SLC7A1, PARN, PARG | LMNA 333/4885ALDH1A1 4841/4885TSHR 1244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.