Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973798 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL5074351 | 0.80 | CYP3A4 (0.61) | SMN1; SMN2ALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL1251762 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL19417920 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL18930268 | 0.78 | LMNA (0.44) | SMN1; SMN2ALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL1133304 | 0.76 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL24218222 | 0.75 | LMNA (0.41) | SMN1; SMN2ALDH1A1L3MBTL1TDP1LMNA | |
| SCHEMBL21023213 | 0.75 | LMNA (0.48) | SMN1; SMN2ALDH1A1L3MBTL1TDP1HIF1A | |
| SCHEMBL14930874 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1L3MBTL1TDP1CYP3A4 | |
| SCHEMBL25590041 | 0.72 | LMNA (0.45) | SMN1; SMN2ALDH1A1L3MBTL1TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170157104-A1 | Anti-Viral Compounds | ABBVIE INC. (US) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157104-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | SMN1; SMN2 4141/4885ALDH1A1 2858/4885L3MBTL1 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.