Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12545919 | 0.85 | HTT (0.57) | HPGDHCRTR1HCRTR2HTTHSD17B10 | |
| SCHEMBL18930366 | 0.81 | HSP90AA1 (0.62) | ALDH1A1HSP90AA1HSP90AB1TSHRKMT2A | |
| SCHEMBL9124992 | 0.80 | ALDH1A1 (0.56) | HPGDHTTALDH1A1HSD17B10RAB9A | |
| SCHEMBL25719160 | 0.76 | EPHX1 (0.52) | HPGDHTTALDH1A1HSD17B10TSHR | |
| SCHEMBL8804661 | 0.75 | HTT (0.54) | HPGDHTTALDH1A1HSD17B10RAB9A | |
| SCHEMBL23761301 | 0.74 | NAMPT (0.46) | HCRTR1HCRTR2HSP90AA1HSP90AB1P2RX7 | |
| SCHEMBL22019205 | 0.74 | HPGD (0.46) | HPGDHTTALDH1A1HSD17B10RAB9A | |
| SCHEMBL19768977 | 0.73 | HTT (0.51) | HPGDHTTALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL12545976 | 0.73 | HTT (0.51) | HPGDHTTALDH1A1TSHRMEN1 | |
| SCHEMBL12545828 | 0.73 | HTT (0.55) | HPGDHCRTR1HCRTR2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093543-A2 | ANTI-BACTERIAL COMPOUNDS | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |