Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125083 | 0.86 | KMT2A (0.59) | ALDH1A1KMT2ATDP1GAAHPGD | |
| SCHEMBL9123908 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2ATDP1GAATYR | |
| SCHEMBL9124217 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2ATDP1GAAHPGD | |
| SCHEMBL9124250 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KMT2ATDP1GAATYR | |
| SCHEMBL18930367 | 0.80 | HPGD (0.49) | ALDH1A1KMT2AHPGDRAB9AHSD17B10 | |
| SCHEMBL9122348 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KMT2ATDP1GAATSHR | |
| SCHEMBL9123049 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KMT2ATDP1GAATYR | |
| SCHEMBL9122324 | 0.79 | LMNA (0.54) | ALDH1A1KMT2ATDP1GAATSHR | |
| SCHEMBL9124951 | 0.79 | KMT2A (0.50) | ALDH1A1KMT2ATDP1GAATYR | |
| SCHEMBL9124615 | 0.79 | MAPT (0.57) | ALDH1A1KMT2ATDP1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413997-A | For treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5112867-A | Osteoporosis Treatment | KYOWA HAKKO GOGYO CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |