Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932583 | 1.00 | TSHR (0.37) | TSHRPDCD4PRKCACHRM2CHRM4 | |
| SCHEMBL12563679 | 0.88 | TSHR (0.42) | TSHRPRKCACHRM2CHRM4CHRM1 | |
| SCHEMBL15500033 | 0.87 | TSHR (0.40) | TSHRPDCD4PRKCACHRM2CHRM4 | |
| SCHEMBL12904345 | 0.87 | TSHR (0.35) | TSHRPDCD4PRKCACHRM2CHRM4 | |
| SCHEMBL20067009 | 0.86 | PRKCA (0.35) | PRKCA | |
| SCHEMBL820957 | 0.84 | TSHR (0.37) | TSHRPDCD4PRKCACHRM2CHRM4 | |
| SCHEMBL13120280 | 0.84 | TSHR (0.37) | TSHRPDCD4PRKCACHRM2CHRM4 | |
| SCHEMBL18932585 | 0.83 | PRKCA (0.34) | TSHRPDCD4PRKCACHRM2CHRM4 | |
| SCHEMBL13096216 | 0.80 | TSHR (0.32) | TSHRPDCD4CHRM2CHRM4CHRM1 | |
| SCHEMBL13096214 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158611-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | ALCON INC. (CH) | 2017-06-08 | — | — | US | disclosed |
| US-20170158611-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | ALCON INC. (CH) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158611-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | CRYZ, UACA, XRCC5 | TSHR 3980/4885PDCD4 2431/4885PRKCA 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.