SCHEMBL18933192

SCHEMBL18933192

O=C(CC(Cc1ccccc1)NC(=O)C1CCCN1C(=O)C1CCCN1)NC(CO)Cc1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CTRB1 P17538 1/20 0.42
▸ TACR1 P25103 3/20 0.42
▸ CTSC P53634 1/20 0.39
▸ NTMT1 Q9BV86 1/20 0.38
▸ USP2 O75604 1/20 0.37
▸ L3MBTL1 Q9Y468 2/20 0.37
▸ REN P00797 3/20 0.37
▸ DPP4 P27487 2/20 0.37
▸ DPP8 Q6V1X1 2/20 0.37
▸ LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14903256 0.92 TACR1 (0.45) CTRB1TACR1CTSCNTMT1REN
SCHEMBL14903396 0.92 TACR1 (0.45) CTRB1TACR1CTSCNTMT1REN
SCHEMBL6880651 0.86 CTRB1 (0.49) CTRB1CTSCRENDPP4DPP8
SCHEMBL6879220 0.86 CTRB1 (0.49) CTRB1CTSCRENDPP4DPP8
SCHEMBL6876472 0.84 CTRB1 (0.48) CTRB1TACR1CTSCRENDPP4
SCHEMBL6880524 0.84 CTRB1 (0.48) CTRB1TACR1CTSCRENDPP4
SCHEMBL6878588 0.84 CTRB1 (0.48) CTRB1TACR1CTSCRENDPP4
SCHEMBL6876603 0.84 CTRB1 (0.48) CTRB1TACR1CTSCRENDPP4
SCHEMBL14906471 0.84 CTRB1 (0.48) CTRB1TACR1CTSCRENDPP4
SCHEMBL14906464 0.84 CTRB1 (0.48) CTRB1TACR1CTSCRENDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10238713-B2 Cyclic tetrapeptides and therapeutic applications thereof LODZ UNIVERSITY OF TECHNOLOGY (PL) 2019-03-26 — — US disclosed
US-20170157204-A1 CYCLIC TETRAPEPTIDES AND THERAPEUTIC APPLICATIONS THEREOF LODZ UNIVERSITY OF TECHNOLOGY (PL) 2017-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170157204-A1 CYCLIC TETRAPEPTIDES AND THERAPEUTIC APPLICATIONS THEREOF PNISR, APLNR, VIP CTRB1 1251/4885TACR1 81/4885CTSC 419/4885
US-10238713-B2 Cyclic tetrapeptides and therapeutic applications thereof PNISR, APLNR, VIP CTRB1 1251/4885TACR1 81/4885CTSC 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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