Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18934568 | 0.84 | GSK3A (0.41) | ALDH1A1MAPK8HTR7L3MBTL1PGR | |
| SCHEMBL18934549 | 0.82 | GSK3A (0.40) | ALDH1A1MAPK8HTR7L3MBTL1PGR | |
| SCHEMBL18934612 | 0.82 | ALDH1A1 (0.38) | NTRK1NTRK3NTRK2ALDH1A1MAPK8 | |
| SCHEMBL20527922 | 0.82 | ALDH1A1 (0.41) | NTRK1NTRK3NTRK2ALDH1A1MAPK8 | |
| SCHEMBL18934351 | 0.80 | LMNA (0.38) | ALDH1A1L3MBTL1LMNAMAPTMAPK1 | |
| SCHEMBL18934889 | 0.73 | SLC6A2 (0.39) | MAPK8HTR7L3MBTL1PGRMAPK9 | |
| SCHEMBL18934550 | 0.72 | HTR7 (0.38) | ALDH1A1MAPK8HTR7PGRMAPK9 | |
| SCHEMBL6362698 | 0.72 | GSK3A (0.56) | NTRK1NTRK3NTRK2MAPK8HTR7 | |
| SCHEMBL18934691 | 0.71 | KDM4E (0.46) | ALDH1A1MAPK8L3MBTL1PGRMAPK9 | |
| SCHEMBL18934336 | 0.70 | GAA (0.43) | ALDH1A1MAPK8PGRMAPK9GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093958-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | WO | disclosed |