SCHEMBL1893469

SCHEMBL1893469

Cc1cc(Cl)cc(Cl)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
TSHR P16473 4/20 0.65
HSD17B10 Q99714 4/20 0.65
CYP3A4 P08684 2/20 0.65
RECQL P46063 2/20 0.65
HPGD P15428 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TTR P02766 2/20 0.50
MAPT P10636 2/20 0.50
THRB P10828 2/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.50
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
NR1I2 O75469 1/20 0.50
SLC22A3 O75751 1/20 0.50
EGFR P00533 1/20 0.50
LMNA P02545 1/20 0.50
ESR1 P03372 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30804415 1.00 ALDH1A1 (0.65) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL1182540 0.86 CA1 (0.58) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL14644985 0.81 HSD17B10 (0.77) ALDH1A1TSHRHSD17B10CYP3A4RECQL
Methyl Alcohol SCHEMBL28184301 0.80 HSD17B10 (0.88) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL184648 0.80 HSD17B10 (1.00) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL8872103 0.80 HSD17B10 (1.00) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL4396495 0.79 ALDH1A1 (0.52) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL3788864 0.79 CYP3A4 (0.59) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL2933421 0.79 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL15064803 0.79 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11158903-B2 Separators, articles and methods of making thereof SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-26 US claimed
EP-3497735-A1 SEPARATORS, ARTICLES AND METHODS OF MAKING THEREOF SABIC Global Technologies B.V. (NL) 2019-06-19 EP claimed
US-20190181413-A1 SEPARATORS, ARTICLES and METHODS OF MAKING THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-06-13 US claimed
US-20160208418-A1 SHEAR SPUN SUB-MICROMETER FIBERS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2016-07-21 US claimed
EP-3033447-A1 SHEAR SPUN SUB-MICROMETER FIBERS SABIC Global Technologies B.V. (NL) 2016-06-22 EP claimed
EP-2880701-A1 HIGH TEMPERATURE MELT INTEGRITY SEPARATOR SABIC Global Technologies B.V. (NL) 2015-06-10 EP claimed
WO-2014020545-A1 HIGH TEMPERATURE MELT INTEGRITY SEPARATOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-02-06 WO claimed
US-20140030608-A1 HIGH TEMPERATURE MELT INTEGRITY SEPARATOR SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-30 US claimed
US-7439291-B2 Solvent-resistant membranes from solvent-inert polyimides and polyketones GENERAL ELECTRIC COMPANY (US) 2008-10-21 US claimed
US-20070060688-A1 Solvent-resistant membranes from solvent-inert polyimides and polyketones GENERAL ELECTRIC COMPANY 2007-03-15 US claimed
EP-1066269-B1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA NV (BE) 2005-05-11 EP claimed
US-20020115668-A1 Trisubstituted 1,3,5-triazine derivatives DAEYAERT FREDERIK FRANS DESIRE (BE) 2002-08-22 US claimed
EP-1066269-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 2001-01-10 EP claimed
US-6150360-A ADMINISTERING TO A PATIENT SUFFERING FROM HUMAN IMMUNODEFICIENCY VIRUS INFECTION A TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVE JANSSEN PHARMACEUTICA N.V. (BE) 2000-11-21 US claimed
WO-1999050256-A1 TRISUBSTITUTED 1,3,5-TRIAZINE DERIVATIVES FOR TREATMENT OF HIV INFECTIONS JANSSEN PHARMACEUTICA N.V. (BE) 1999-10-07 WO claimed
EP-0243126-B1 METHOD OF MEASURING HYDROGEN PEROXIDE OR OF MEASURING AN ENZYME OR BIOCHEMICAL SUBSTRATE LIBERATING THE PEROXIDE SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1992-08-12 EP claimed
US-4039587-A Method of preparing polynuclear, halogenated, aromatic benzyl ethers DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-08-02 US claimed
JP-4283502-A None JP disclosed
US-3962180-A COPPER, MANGANESE OR COBALT AND AN AMINE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1976-06-08 US disclosed
US-3954919-A INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115668-A1 Trisubstituted 1,3,5-triazine derivatives XDH, CCR5, CXCR1 ALDH1A1 3722/4885TSHR 656/4885HSD17B10 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.