Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18934518 | 0.82 | NQO2 (0.45) | KIF11KDM4EALDH1A1HPGDSMN1; SMN2 | |
| Carbazole SCHEMBL16433320 | 0.81 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL17967450 | 0.77 | PARP14 (0.38) | KIF11KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18934280 | 0.76 | KIF11 (0.45) | KIF11KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL16066239 | 0.76 | CYP1A2 (0.45) | KIF11KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1698065 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL18934884 | 0.75 | AHR (0.46) | KIF11KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18934520 | 0.75 | AHR (0.50) | KIF11KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16066433 | 0.75 | CYP1A2 (0.47) | KIF11KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18934275 | 0.75 | KIF11 (0.44) | KIF11KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093958-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | WO | disclosed |