SCHEMBL18935567

SCHEMBL18935567

C1=CC=Cc2ccccc2N=1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40442 0.74
SCHEMBL18760604 0.74
SCHEMBL22567054 0.72 GAA (0.32)
SCHEMBL23933294 0.72
SCHEMBL654847 0.71
SCHEMBL21515908 0.69
SCHEMBL21367604 0.69 LMNA (0.32)
SCHEMBL25450738 0.69 ALDH1A1 (0.32)
SCHEMBL211354 0.68 TRPA1 (0.30)
SCHEMBL379614 0.67 TRPA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119186638-A Catalyst for preparing dialkyl carbonate, preparation method and application thereof 中国石油化工股份有限公司 2024-12-27 CN claimed
CN-113387885-B Preparation method of 1-benzazepine compound 兰州大学 2023-01-03 CN claimed
CN-113387885-A Preparation method of 1-benzazepine compound 兰州大学 2021-09-14 CN claimed
EP-0119954-B1 3-AMINO-1-BENZAZEPIN-2-ONE-1-ALCANOIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR PHARMACEUTICAL PREPARATION AS WELL AS THEIR THERAPEUTIC USE CIBA-GEIGY AG (CH) 1990-03-14 EP claimed
US-12624111-B2 Methods for treating metastatic colon cancer with leronlimab CYTODYN INC. (US) 2026-05-12 US disclosed
US-20250224340-A1 Colorimetric Detection of Organic Amines Using Metal-Organic Frameworks THE JOHNS HOPKINS UNIVERSITY 2025-07-10 US disclosed
CN-119186638-A Catalyst for preparing dialkyl carbonate, preparation method and application thereof 中国石油化工股份有限公司 2024-12-27 CN disclosed
CN-116891435-A Method for synthesizing benzazepine derivative 浙江理工大学 2023-10-17 CN disclosed
CN-109996807-B SCN9A antisense oligonucleotides 奥利通公司 2023-07-28 CN disclosed
WO-2023284654-A1 ORGANIC HETEROCYCLIC COMPOUND AND APPLICATION THEREOF IN ORGANIC LIGHT EMITTING DIODE 浙江光昊光电科技有限公司 2023-01-19 WO disclosed
CN-113387885-B Preparation method of 1-benzazepine compound 兰州大学 2023-01-03 CN disclosed
CN-113387885-B Preparation method of 1-benzazepine compound 兰州大学 2023-01-03 CN disclosed
US-5747487-A N-(4-((4,5-DIHYDRO-6H-THIAZOL(5,4-D)(1)BENZAZEPIN-6-YL) -CARBONYL)PHENYL)BENZAMIDES; DISEASES CHARATERIZED BY EXCESS RENAL ABSORPTION OF WATER, E.G. CONGESTIVE HEART DISEASE, HYERTENSION; OXYTOCIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1998-05-05 US disclosed
WO-1998002423-A1 PROCESS FOR PREPARING 1-SUBSTITUTED 4-CYANO-1,2,3-TRIAZOLES NOVARTIS AG (CH) 1998-01-22 WO disclosed
US-5693635-A TREATMENT OF DISEASES CHARACTERIZED BY EXCESS RENAL ABSORPTION OF WATER; CONGESTIVE HEART FAILURE, NEPHROTIC SYNDROME AMERICAN CYANAMID COMPANY (US) 1997-12-02 US disclosed
US-5686445-A Pyridobenzoxazepine and pyridobenzothiazepine vasopressin antagonists AMERICAN CYANAMID COMPANY (US) 1997-11-11 US disclosed
EP-0434844-A1 NEW CYCLIC ANTHRANILIC ACID DERIVATIVE AND METHOD OF PRODUCING THE SAME KYORIN PHARMACEUTICAL CO., LTD. (JP) 1991-07-03 EP disclosed
EP-0130538-A3 COMPOSITION FOR TREATING ALLERGY USV PHARMACEUTICAL CORPORATION (US) 1985-12-04 EP disclosed
EP-0130538-A2 Composition for treating allergy USV PHARMACEUTICAL CORPORATION (US) 1985-01-09 EP disclosed
EP-0130538-A2 Composition for treating allergy USV PHARMACEUTICAL CORPORATION (US) 1985-01-09 EP disclosed