SCHEMBL1893620

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28482288	0.88	RNASEH1 (0.68)	RNASEH1TP53MAPTNFKB1NFKB2
	SCHEMBL1888278	0.82	HDAC1 (0.61)	NPC1RAB9AHDAC1HDAC8HDAC6
	SCHEMBL3093607	0.81	RNASEH1 (0.59)	RNASEH1TP53MAPTNFKB1NFKB2
	SCHEMBL3950590	0.80	RNASEH1 (1.00)	RNASEH1TP53MAPTNFKB1NFKB2
	SCHEMBL1885783	0.78	HDAC1 (0.55)	RNASEH1MAPTNFKB1NFKB2RELA
	SCHEMBL31110177	0.77	MAPT (1.00)	RNASEH1TP53MAPTNFKB1NFKB2
	SCHEMBL28513667	0.77	RNASEH1 (0.55)	RNASEH1TP53MAPTNFKB1NFKB2
	SCHEMBL11454295	0.76	CYP1A2 (0.68)	RNASEH1TP53MAPTNFKB1NFKB2
	SCHEMBL1890491	0.75	HDAC8 (0.64)	MAPTSMN1; SMN2NPC1RAB9AHDAC1
	Benzohydroxamate SCHEMBL133061	0.74	HDAC8 (1.00)	HDAC1HDAC8HDAC6HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.