Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466989 | 0.87 | SIGMAR1 (0.57) | SIGMAR1PARP1SMN1; SMN2HTR1A | |
| SCHEMBL18936739 | 0.84 | SIGMAR1 (0.66) | SIGMAR1PARP1MEN1KMT2AHTR1A | |
| SCHEMBL7303423 | 0.83 | QDPR (0.51) | SIGMAR1ALDH1A1PARP1CYP1A2HTR1A | |
| SCHEMBL5536604 | 0.83 | SIGMAR1 (0.65) | SIGMAR1PARP1MEN1KMT2AHTR1A | |
| SCHEMBL7304853 | 0.82 | SIGMAR1 (0.58) | SIGMAR1HTR1A | |
| SCHEMBL5541688 | 0.82 | SIGMAR1 (0.67) | SIGMAR1PARP1MEN1KMT2AHTR1A | |
| SCHEMBL5539408 | 0.81 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1KDM4EPARP1MEN1 | |
| SCHEMBL5536761 | 0.81 | SIGMAR1 (0.65) | SIGMAR1PARP1MEN1KMT2AHTR1A | |
| SCHEMBL11823875 | 0.80 | SIGMAR1 (0.60) | SIGMAR1ALDH1A1KDM4EPARP1MEN1 | |
| SCHEMBL6367251 | 0.80 | SIGMAR1 (0.61) | SIGMAR1PARP1MEN1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149817-A | Psychotropic agents | SHIONOGI & CO., LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0445701-A1 | Novel tetrahydropyridine derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |