Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | GRK5 | P34947 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22879395 | 0.78 | HSD17B3 (0.47) | TSHRMEN1KMT2APOLBLMNA | |
| SCHEMBL15762375 | 0.78 | L3MBTL1 (0.47) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4428563 | 0.77 | TSHR (0.49) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL474484 | 0.77 | CYP11B1 (0.51) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL30581468 | 0.77 | TSHR (0.53) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL2748218 | 0.77 | TSHR (0.53) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7350158 | 0.77 | ALOX12 (0.47) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14615631 | 0.75 | KMO (0.55) | TSHRMEN1KMT2APOLBHTT | |
| SCHEMBL6362106 | 0.74 | HPGD (0.56) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL19393139 | 0.73 | L3MBTL1 (0.46) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093545-A1 | ANTI-BACTERIAL COMPOUNDS BASED ON AMINO-GOLD PHOSPHINE COMPLEXES | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |