Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997425 | 0.87 | MTNR1A (0.60) | MTNR1AMTNR1BDYRK1ABRD4 | |
| SCHEMBL17294058 | 0.83 | CYP2A6 (0.44) | MTNR1AMTNR1BDYRK1ABRD4CNR2 | |
| SCHEMBL18927041 | 0.83 | BRD4 (0.49) | MTNR1AMTNR1BDYRK1ABRD4CNR2 | |
| SCHEMBL18935520 | 0.82 | BRD4 (0.49) | MTNR1AMTNR1BDYRK1ABRD4DRD2 | |
| SCHEMBL18917851 | 0.81 | BRD4 (0.51) | MTNR1AMTNR1BBRD4 | |
| SCHEMBL18938905 | 0.80 | CAMK2D (0.48) | DYRK1ABRD4CNR2DRD2 | |
| SCHEMBL18918073 | 0.80 | CYP2A6 (0.43) | MTNR1AMTNR1BBRD4DRD2 | |
| SCHEMBL18935522 | 0.78 | MTNR1A (0.51) | MTNR1AMTNR1BDYRK1ABRD4 | |
| SCHEMBL3417837 | 0.77 | MTNR1A (0.50) | MTNR1AMTNR1BBRD4 | |
| SCHEMBL24414562 | 0.76 | MTNR1A (0.42) | MTNR1AMTNR1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096045-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. (US) | 2017-06-08 | — | — | WO | disclosed |