Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22439524 | 0.98 | HTR7 (0.48) | HTR7HTR6KDM4CHTR2AHTR2C | |
| SCHEMBL2266129 | 0.85 | DGAT1 (0.43) | HTR7KDM4CHTR2AHTR2CDRD2 | |
| SCHEMBL565845 | 0.85 | GRM2 (0.42) | HTR7HTR2AHTR2CDRD2SLC6A4 | |
| SCHEMBL10064858 | 0.85 | GRM2 (0.42) | HTR7HTR2AHTR2CDRD2SLC6A4 | |
| SCHEMBL10064856 | 0.85 | GRM2 (0.42) | HTR7HTR2AHTR2CDRD2SLC6A4 | |
| SCHEMBL31324662 | 0.85 | HTR7 (0.51) | HTR7HTR6DRD2SLC6A4NOS3 | |
| SCHEMBL2264672 | 0.84 | NOS3 (0.48) | HTR7HTR6HTR2AHTR2CDRD2 | |
| SCHEMBL565952 | 0.84 | HTR7 (0.38) | HTR7KDM4CHTR2AHTR2CDRD2 | |
| Methane SCHEMBL28163314 | 0.83 | HTR7 (0.50) | HTR7HTR6DRD2SLC6A4NOS3 | |
| SCHEMBL26676818 | 0.83 | HTR7 (0.47) | HTR7HTR6DRD2SLC6A4NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017096045-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. (US) | 2017-06-08 | — | — | WO | disclosed |