Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BMP1 | P13497 | 5/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16710126 | 0.93 | BMP1 (0.47) | RAB9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16710089 | 0.91 | CYP1A2 (0.56) | RAB9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16706677 | 0.91 | NPC1 (0.50) | RAB9ANPC1POLBBCHESMN1; SMN2 | |
| SCHEMBL16706685 | 0.90 | BCHE (0.43) | POLBBMP1BCHESMN1; SMN2ALDH1A1 | |
| SCHEMBL18427194 | 0.90 | NPC1 (0.49) | RAB9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16710129 | 0.89 | BCHE (0.45) | RAB9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16710130 | 0.88 | RAB9A (0.48) | RAB9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16710127 | 0.88 | RAB9A (0.48) | RAB9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16710087 | 0.88 | SMN1; SMN2 (0.61) | RAB9ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16710100 | 0.88 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951033-B2 | Tertiary amines for use in the treatment of cardiac disorders | UNIVERSITETET I OSLO (NO) | 2018-04-24 | — | — | US | disclosed |
| US-20170158657-A1 | TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS | UNIVERSITETET I OSLO (NO) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158657-A1 | TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS | TNNI3, TNNT2, MYLK2 | RAB9A 1672/4885CYP1A2 2116/4885CYP3A4 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.