Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18939743 | 0.87 | GAA (0.59) | NPC1RAB9ASMN1; SMN2GAAACHE | |
| SCHEMBL18920485 | 0.87 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL18938489 | 0.85 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2GAAACHE | |
| SCHEMBL25440287 | 0.80 | GAA (0.53) | NPC1RAB9ASMN1; SMN2GAAACHE | |
| SCHEMBL23405305 | 0.80 | MAPK1 (0.41) | NPC1RAB9ASMN1; SMN2GAAKCNN4 | |
| SCHEMBL29781813 | 0.80 | ACHE (0.62) | NPC1RAB9ASMN1; SMN2GAAACHE | |
| SCHEMBL321561 | 0.80 | ACHE (0.62) | NPC1RAB9ASMN1; SMN2GAAACHE | |
| SCHEMBL18938787 | 0.77 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2GAACASP3 | |
| SCHEMBL18938463 | 0.77 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL22357691 | 0.75 | GAA (0.48) | NPC1RAB9ASMN1; SMN2GAAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200262799-A1 | PROCESS FOR PREPARING FUNCTIONALIZED 1,2,4,5-TETRAZINE COMPOUNDS | UNIVERSITE DE BOURGOGNE (FR) | 2020-08-20 | — | — | US | disclosed |
| WO-2017093263-A1 | PROCESS FOR PREPARING FUNCTIONALIZED 1,2,4,5-TETRAZINE COMPOUNDS | UNIVERSITE DE BOURGOGNE (FR) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262799-A1 | PROCESS FOR PREPARING FUNCTIONALIZED 1,2,4,5-TETRAZINE COMPOUNDS | CYP4Z1, CYP4F12, CYP3A5 | NPC1 2706/4885RAB9A 2920/4885SMN1; SMN2 2682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.