Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22283557 | 0.98 | SIGMAR1 (0.40) | SIGMAR1KDM1ALGMNTLR8TLR7 | |
| SCHEMBL18940337 | 0.91 | SIGMAR1 (0.40) | SIGMAR1KDM1ALGMNACHECYP2A13 | |
| SCHEMBL29974812 | 0.86 | ACHE (0.49) | SIGMAR1ACHE | |
| SCHEMBL16341499 | 0.86 | ACHE (0.49) | SIGMAR1ACHE | |
| SCHEMBL18940321 | 0.84 | ACHE (0.47) | SIGMAR1ACHE | |
| SCHEMBL18940359 | 0.83 | NOS3 (0.47) | SIGMAR1 | |
| SCHEMBL18940342 | 0.82 | TLR8 (0.37) | SIGMAR1KDM1ATLR8TLR7ACHE | |
| Hydrochloric Acid SCHEMBL22283558 | 0.82 | NOS3 (0.46) | SIGMAR1ACHE | |
| SCHEMBL12006407 | 0.82 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL29973392 | 0.82 | SIGMAR1 (0.50) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004674-B2 | Substituted p-phenylenediamines as new oxidation dye precursor products of the developer type | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | claimed |
| US-20170165166-A1 | SUBSTITUTED P-PHENYLENEDIAMINES AS NEW OXIDATION DYE PRECURSOR PRODUCTS OF THE DEVELOPER TYPE | HENKEL AG & CO. KGAA (DE) | 2017-06-15 | — | — | US | claimed |
| EP-3687978-A1 | PARA-PHENYLENEDIAMINE BASES WITH CATIONIC HETEROCYCLES, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES | L'Oreal (FR) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019063696-A1 | PARA-PHENYLENEDIAMINE BASES WITH CATIONIC HETEROCYCLES, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES | L' OREAL (FR) | 2019-04-04 | — | — | WO | disclosed |
| US-10004674-B2 | Substituted p-phenylenediamines as new oxidation dye precursor products of the developer type | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | disclosed |
| US-10004674-B2 | Substituted p-phenylenediamines as new oxidation dye precursor products of the developer type | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | disclosed |
| US-10004674-B2 | Substituted p-phenylenediamines as new oxidation dye precursor products of the developer type | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | disclosed |
| US-20170165166-A1 | SUBSTITUTED P-PHENYLENEDIAMINES AS NEW OXIDATION DYE PRECURSOR PRODUCTS OF THE DEVELOPER TYPE | HENKEL AG & CO. KGAA (DE) | 2017-06-15 | — | — | US | disclosed |
| US-20170165166-A1 | SUBSTITUTED P-PHENYLENEDIAMINES AS NEW OXIDATION DYE PRECURSOR PRODUCTS OF THE DEVELOPER TYPE | HENKEL AG & CO. KGAA (DE) | 2017-06-15 | — | — | US | disclosed |
| US-20170165166-A1 | SUBSTITUTED P-PHENYLENEDIAMINES AS NEW OXIDATION DYE PRECURSOR PRODUCTS OF THE DEVELOPER TYPE | HENKEL AG & CO. KGAA (DE) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004674-B2 | Substituted p-phenylenediamines as new oxidation dye precursor products of the developer type | KRT18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-0 | SIGMAR1 1580/4885KDM1A 1363/4885LGMN 4335/4885 |
| US-20170165166-A1 | SUBSTITUTED P-PHENYLENEDIAMINES AS NEW OXIDATION DYE PRECURSOR PRODUCTS OF THE DEVELOPER TYPE | KRT18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-0 | SIGMAR1 1580/4885KDM1A 1363/4885LGMN 4335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.