Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 3/20 | 0.31 |
| ▸ | ARG2 | P78540 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25564414 | 0.80 | FFAR3 (0.46) | FFAR3LMNAMAPK1NPSR1ARG1 | |
| SCHEMBL12002080 | 0.76 | FFAR3 (0.54) | FFAR3LMNAPOLBMAPK1NPSR1 | |
| SCHEMBL31645383 | 0.75 | BTK (0.54) | NFKB1 | |
| SCHEMBL31645007 | 0.75 | BTK (0.54) | NFKB1 | |
| SCHEMBL31645005 | 0.75 | BTK (0.54) | NFKB1 | |
| SCHEMBL28245170 | 0.75 | BTK (0.54) | NFKB1 | |
| SCHEMBL16665211 | 0.75 | BTK (0.54) | NFKB1 | |
| SCHEMBL18069837 | 0.75 | CYP1A2 (0.52) | FFAR3LMNACYP1A2MAPK1NPSR1 | |
| Hydrochloric Acid SCHEMBL17317623 | 0.75 | FFAR3 (0.52) | FFAR3LMNAPOLBMAPK1NPSR1 | |
| SCHEMBL709809 | 0.75 | FFAR3 (0.46) | FFAR3LMNACYP1A2MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105207-B1 | GPR142 AGONIST COMPOUNDS | LILLY CO ELI (US) | 2018-08-22 | — | — | EP | disclosed |
| US-9861613-B2 | GPR142 agonist compounds | ELI LILLY AND COMPANY (US) | 2018-01-09 | — | — | US | disclosed |
| US-20170165234-A1 | GPR142 Agonist Compounds | ELI LILLY AND COMPANY | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170165234-A1 | GPR142 Agonist Compounds | GPR3, GPR142, GPR27 | FFAR3 19/4885LMNA 4032/4885POLB 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.