Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.82 |
| ▸ | CA2 | P00918 | 3/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759729 | 0.90 | CA1 (1.00) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL16261609 | 0.84 | ALDH1A1 (0.61) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL14009917 | 0.84 | CA1 (0.62) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL2585599 | 0.83 | ALDH1A1 (0.60) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL31005217 | 0.81 | CYP1A2 (0.78) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL4788494 | 0.81 | CYP1A2 (0.78) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL3563963 | 0.78 | CYP1A2 (0.68) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL1101136 | 0.78 | LMNA (0.55) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL18539244 | 0.78 | LMNA (0.55) | ALDH1A1MEN1KMT2AHTTLMNA | |
| SCHEMBL18539295 | 0.78 | LMNA (0.55) | ALDH1A1MEN1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498611-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | Receptos, Inc. (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011060389-A1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS | RECEPTOS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |