Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.45 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.43 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.43 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009191 | 0.89 | HDAC4 (0.47) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| SCHEMBL701212 | 0.84 | NPC1 (0.51) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| SCHEMBL2936175 | 0.84 | NPC1 (0.51) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| SCHEMBL591280 | 0.84 | NPC1 (0.51) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| SCHEMBL676271 | 0.84 | HDAC1 (0.51) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| SCHEMBL676270 | 0.84 | HDAC1 (0.51) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| SCHEMBL29458758 | 0.84 | HDAC1 (0.51) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| SCHEMBL10583019 | 0.84 | HDAC1 (0.51) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| SCHEMBL24612904 | 0.83 | KDM4E (0.56) | HDAC4MEF2DHDAC1HDAC3HDAC7 | |
| Hydrochloric Acid SCHEMBL593062 | 0.83 | NPC1 (0.50) | HDAC4MEF2DHDAC1HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158836-A1 | ORDERED MACROPOROUS HYDROGELS FOR BIORESPONSIVE PROCESSES | CARNEGIE MELLON UNIVERSITY | 2017-06-08 | — | — | US | disclosed |