Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764316 | 0.80 | ACE2 (0.44) | ACE2ALOX15CARM1PRMT6PRMT8 | |
| SCHEMBL10187342 | 0.79 | — | — | |
| SCHEMBL20551362 | 0.78 | ACE2 (0.43) | ACE2GNAI3GNAO1GNAI1ALOX15 | |
| SCHEMBL10501491 | 0.77 | CARM1 (0.54) | ACE2CARM1PRMT6PRMT8 | |
| SCHEMBL14500286 | 0.73 | HSD17B10 (0.53) | ACE2ALOX15CARM1PRMT6PRMT8 | |
| SCHEMBL696834 | 0.73 | KEAP1 (0.52) | — | |
| SCHEMBL22286063 | 0.72 | CYP2C19 (0.39) | ACE2 | |
| Hydrochloric Acid SCHEMBL165528 | 0.71 | KEAP1 (0.50) | — | |
| SCHEMBL13494978 | 0.70 | ALOX15 (0.77) | ACE2GNAI3GNAO1GNAI1ALOX15 | |
| SCHEMBL17610281 | 0.70 | SIGMAR1 (0.37) | ACE2CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953457-B1 | ERK INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2020-04-08 | — | — | EP | disclosed |
| EP-3039083-B1 | DYE MIXTURES OF METAL-FREE REACTIVE DYES, PRODUCTION AND USE | DYSTAR COLOURS DISTRIB GMBH (DE) | 2017-06-07 | — | — | EP | disclosed |