Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 4/20 | 0.30 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027651 | 0.80 | BRPF1 (0.51) | BRPF1SMN1; SMN2KAT2BHTR5AHSD17B10 | |
| SCHEMBL9537170 | 0.75 | DRD4 (0.36) | LMNASMN1; SMN2OPRK1DRD4DRD2 | |
| SCHEMBL30935794 | 0.74 | BRPF1 (0.44) | BRPF1LMNASMN1; SMN2OPRK1PDE4D | |
| SCHEMBL29990699 | 0.74 | TSPO (0.34) | LMNASMN1; SMN2OPRK1DRD4DRD2 | |
| SCHEMBL21379279 | 0.74 | TSPO (0.34) | LMNASMN1; SMN2OPRK1DRD4DRD2 | |
| SCHEMBL1495860 | 0.74 | TSPO (0.37) | LMNASMN1; SMN2OPRK1DRD4DRD2 | |
| SCHEMBL22050042 | 0.72 | BRPF1 (0.60) | BRPF1LMNASMN1; SMN2OPRK1PDE4D | |
| SCHEMBL9539100 | 0.64 | DRD4 (0.36) | DRD4DRD2CHRM1DRD3ADRA2A | |
| SCHEMBL2629041 | 0.63 | TSHR (0.34) | SMN1; SMN2DRD4DRD2CHRM1ADRA2A | |
| SCHEMBL30935803 | 0.63 | BRPF1 (0.44) | BRPF1LMNASMN1; SMN2OPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |