Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 5/20 | 0.33 |
| ▸ | HTR5A | P47898 | 5/20 | 0.33 |
| ▸ | HTR3A | P46098 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.33 |
| ▸ | HTR3B | O95264 | 2/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29990699 | 1.00 | TSPO (0.34) | TSPODRD4HTR5AHTR3AHTR2A | |
| SCHEMBL1495860 | 0.94 | TSPO (0.37) | TSPODRD4HTR5AHTR3AHTR2A | |
| SCHEMBL21379004 | 0.84 | TSPO (0.35) | TSPODRD4HTR5AAVPR1AAVPR2 | |
| SCHEMBL21379060 | 0.83 | CHRM1 (0.34) | TSPOHTR5AAVPR1AOXTRCHRM1 | |
| SCHEMBL21396613 | 0.83 | AVPR1A (0.37) | TSPODRD4AVPR1AOXTRDRD2 | |
| SCHEMBL29990044 | 0.83 | CHRM1 (0.34) | TSPOHTR5AAVPR1AOXTRCHRM1 | |
| SCHEMBL20267114 | 0.82 | PDE3B (0.46) | HTR5AAVPR1AOXTRCHRM1 | |
| SCHEMBL29989621 | 0.82 | PDE3B (0.46) | HTR5AAVPR1AOXTRCHRM1 | |
| SCHEMBL1496015 | 0.81 | TSPO (0.48) | TSPOHTR5AAVPR1AAVPR2OXTR | |
| SCHEMBL22748170 | 0.80 | HTR3E (0.41) | TSPODRD4HTR5AHTR3AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12458648-B2 | Therapeutic compounds and compositions for treating social disorders and substance use disorders | KINOXIS THERAPEUTICS PTY LTD. (AU) | 2025-11-04 | — | — | US | disclosed |
| US-20240245706-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS FOR TREATING SOCIAL DISORDERS AND SUBSTANCE USE DISORDERS | Kinoxis Therapeutics Pty Ltd (AU) | 2024-07-25 | — | — | US | disclosed |
| US-11890287-B2 | Therapeutic compounds and compositions for treating social disorders and substance use disorders | Kinoxis Therapeutics Pty Ltd (AU) | 2024-02-06 | — | — | US | disclosed |
| US-20220362261-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS FOR TREATING SOCIAL DISORDERS AND SUBSTANCE USE DISORDERS | THE UNIVERSITY OF SYDNEY (AU) | 2022-11-17 | — | — | US | disclosed |
| EP-3328864-B1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS FOR TREATING SOCIAL DISORDERS AND SUBSTANCE USE DISORDERS | Kinoxis Therapeutics Pty Ltd (AU) | 2022-09-07 | — | — | EP | disclosed |
| US-11033555-B2 | Therapeutic compounds and compositions for treating social disorders and substance use disorders | Kinoxis Therapeutics Pty Ltd (AU) | 2021-06-15 | — | — | US | disclosed |
| US-11033555-B2 | Therapeutic compounds and compositions for treating social disorders and substance use disorders | Kinoxis Therapeutics Pty Ltd (AU) | 2021-06-15 | — | — | US | disclosed |
| US-20190290658-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS FOR TREATING SOCIAL DISORDERS AND SUBSTANCE USE DISORDERS | Kinoxis Therapeutics Pty Ltd (AU) | 2019-09-26 | — | — | US | disclosed |
| US-20190290658-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS FOR TREATING SOCIAL DISORDERS AND SUBSTANCE USE DISORDERS | Kinoxis Therapeutics Pty Ltd (AU) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245706-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS FOR TREATING SOCIAL DISORDERS AND SUBSTANCE USE DISORDERS | SLC18A2, SLC6A3, CES2 | TSPO 1553/4885DRD4 79/4885HTR5A 73/4885 |
| US-12458648-B2 | Therapeutic compounds and compositions for treating social disorders and substance use disorders | SLC18A2, SLC6A3, CES2 | TSPO 1553/4885DRD4 79/4885HTR5A 73/4885 |
| US-11890287-B2 | Therapeutic compounds and compositions for treating social disorders and substance use disorders | SLC18A2, SLC6A3, CES2 | TSPO 1553/4885DRD4 79/4885HTR5A 73/4885 |
| US-20190290658-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS FOR TREATING SOCIAL DISORDERS AND SUBSTANCE USE DISORDERS | SLC18A2, SLC6A3, CES2 | TSPO 1520/4885DRD4 74/4885HTR5A 76/4885 |
| US-11033555-B2 | Therapeutic compounds and compositions for treating social disorders and substance use disorders | SLC18A2, SLC6A3, CES2 | TSPO 1520/4885DRD4 74/4885HTR5A 76/4885 |
| US-20220362261-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS FOR TREATING SOCIAL DISORDERS AND SUBSTANCE USE DISORDERS | SLC18A2, SLC6A3, CES2 | TSPO 1553/4885DRD4 79/4885HTR5A 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.