Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617262 | 0.81 | FAAH (0.59) | KDM4EALDH1A1FAAHTP53ALK | |
| SCHEMBL578312 | 0.78 | AKR1C3 (0.53) | KDM4EAKR1C3ALDH1A1TP53 | |
| SCHEMBL13353048 | 0.77 | MAPT (0.57) | KDM4EAKR1C3ALDH1A1TP53 | |
| SCHEMBL1136937 | 0.76 | ALDH1A1 (0.52) | KDM4EAKR1C3ALDH1A1TP53 | |
| SCHEMBL18945541 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1FAAHPRMT5WDR77 | |
| SCHEMBL175496 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1FAAHTP53TGFBR1 | |
| SCHEMBL4552322 | 0.75 | AKR1C3 (0.68) | KDM4EAKR1C3ALDH1A1TP53 | |
| SCHEMBL10001302 | 0.75 | KDM4E (0.59) | KDM4EAKR1C3ALDH1A1TP53TGFBR1 | |
| SCHEMBL12551114 | 0.75 | KDM4E (0.59) | KDM4EAKR1C3ALDH1A1 | |
| SCHEMBL12551119 | 0.75 | KDM4E (0.59) | KDM4EAKR1C3ALDH1A1FAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093544-A1 | ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |