Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744121 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| Tetraxetan SCHEMBL2017956 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL3660521 | 0.79 | — | — | |
| SCHEMBL173508 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| Tetraxetan SCHEMBL18018 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| Tetraxetan SCHEMBL2635294 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL6848102 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL3503521 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL321989 | 0.79 | HSD17B10 (0.64) | HSD17B10SLC6A9TSHRS1PR1 | |
| SCHEMBL5945932 | 0.78 | PTGS1 (0.42) | CRBNHSD17B10TSHRKMT2AITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8784777-B2 | Flexibly labeling peptides | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-07-22 | — | — | US | disclosed |
| US-20110104063-A1 | FLEXIBLY LABELING PEPTIDES | US ARMY, SECRETARY OF THE ARMY | 2011-05-05 | — | — | US | disclosed |
| US-7842280-B2 | solid phase peptide synthesis for a peptidyl contrast agent; synthesizing an amino-chelator loaded resin coupling the loaded resin to C-terminus and/or backbone of a peptide, cleaving the amino-chelator-peptide from a resin, and chelating a lanthanide metal; DOTA or DTPA chelate coupled to peptide | CASE WESTERN RESERVE UNIVERSITY (US) | 2010-11-30 | — | — | US | disclosed |
| US-20080089842-A1 | solid phase peptide synthesis for a peptidyl contrast agent; synthesizing an amino-chelator loaded resin coupling the loaded resin to C-terminus and/or backbone of a peptide, cleaving the amino-chelator-peptide from a resin, and chelating a lanthanide metal; DOTA or DTPA chelate coupled to peptide | CASE WESTERN RESERVE UNIVERSITY | 2008-04-17 | — | — | US | disclosed |
| US-6852854-B1 | Preformed carboxylated active ester for labeling biomolecules | PSILOQUEST INC. (US) | 2005-02-08 | — | — | US | disclosed |