SCHEMBL6744121

SCHEMBL6744121

O=C(O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.64
SLC6A9 P48067 1/20 0.47
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
STAT6 P42226 1/20 0.41
S1PR1 P21453 1/20 0.41
GAA P10253 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 1/20 0.38
CYP1A2 P05177 1/20 0.37
MAPK1 P28482 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173508 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL321989 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL3660521 1.00
Tetraxetan SCHEMBL2017956 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL6848102 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL18018 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
SCHEMBL3503521 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL2635294 1.00 HSD17B10 (0.64) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL23647851 0.97 HSD17B10 (0.61) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6
Tetraxetan SCHEMBL15766009 0.97 HSD17B10 (0.61) HSD17B10SLC6A9ALDH1A1SMN1; SMN2STAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 EP disclosed
CN-119684401-A Compounds comprising a linker, a chelator, a ligand binding entity, methods of preparation and uses thereof 赛诺哈勃药业(成都)有限公司 2025-03-25 CN disclosed
EP-4455159-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS WITH BIO-DISTRIBUTION MODIFIER 3B Pharmaceuticals GmbH (DE) 2024-10-30 EP disclosed
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS TRUSTEES OF TUFTS COLLEGE 2024-06-27 US disclosed
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS TRUSTEES OF TUFTS COLLEGE 2024-06-27 US disclosed
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO TRUSTEES OF TUFTS COLLEGE 2023-10-19 US disclosed
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO TRUSTEES OF TUFTS COLLEGE 2023-10-19 US disclosed
EP-4065176-B1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER ITM ISOTOPE TECH MUNICH SE (DE) 2023-10-11 EP disclosed
WO-2023165987-A1 PRECURSOR MARKERS AND RADIOTRACERS WITH THREE OR MORE TARGETING VECTORS FOR THERANOSTICS USED IN NUCLEAR MEDICINE Atoms for Cure GmbH (DE) 2023-09-07 WO disclosed
US-20230248854-A1 METHOD FOR PRODUCING RADIOACTIVE METAL-LABELED ANTIBODY NIHON MEDI-PHYSICS CO., LTD. (JP) 2023-08-10 US disclosed
US-6770020-B2 NEUTRON CAPTURE THERAPY (NCT) USING GADOLINIUM DIETHYLENETRIAMINEPENTAACETIC ACID; TREATING GLIOBLASTOMAS, GLIOMAS WISCONSIN ALUMNI RESEARCH FOUNDATION 2004-08-03 US disclosed
US-20040067924-A1 Actinium-225 complexes and conjugates for targeted radiotherapy FRANK R KEITH (US) 2004-04-08 US disclosed
US-6670456-B2 For therapy of cancer DOW GLOBAL TECHNOLOGIES INC. 2003-12-30 US disclosed
EP-1370301-A2 ACTINIUM-225 COMPLEXES AND CONJUGATES FOR TARGETED RADIOTHERAPY DOW GLOBAL TECHNOLOGIES INC. (US) 2003-12-17 EP disclosed
US-20030086868-A1 Actinium-225 complexes and conjugates for radioimmunotherapy MA DANGSHE (US) 2003-05-08 US disclosed
US-20030049202-A1 Method of using gadolinium neutron capture to treat cancers WISCONSIN ALUMNI RESEARCH FOUNDATION 2003-03-13 US disclosed
US-20030023050-A1 Actinium-225 complexes and conjugates for targeted radiotherapy DOW GLOBAL TECHNOLOGIES INC. 2003-01-30 US disclosed
WO-2002067999-A3 ACTINIUM-225 COMPLEXES AND CONJUGATES FOR TARGETED RADIOTHERAPY DOW GLOBAL TECHNOLOGIES INC (US) 2002-10-24 WO disclosed
WO-2002067999-A2 ACTINIUM-225 COMPLEXES AND CONJUGATES FOR TARGETED RADIOTHERAPY DOW GLOBAL TECHNOLOGIES INC. (US) 2002-09-06 WO disclosed
WO-1995001346-A1 CHELATING COMPOUNDS AKZO NOBEL N.V. (NL) 1995-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO FAP, APC, FIBP HSD17B10 3607/4885SLC6A9 4564/4885ALDH1A1 1322/4885
US-20030023050-A1 Actinium-225 complexes and conjugates for targeted radiotherapy CCR5, CXCR1, CCR9 HSD17B10 2223/4885SLC6A9 2137/4885ALDH1A1 4384/4885
US-20030049202-A1 Method of using gadolinium neutron capture to treat cancers NUCB2, MKI67, GMNN HSD17B10 3436/4885SLC6A9 620/4885ALDH1A1 4571/4885
US-20230248854-A1 METHOD FOR PRODUCING RADIOACTIVE METAL-LABELED ANTIBODY CD4, PTMS, TAC3 HSD17B10 2060/4885SLC6A9 1953/4885ALDH1A1 4185/4885
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS BCL6B, BCL6, BTD HSD17B10 2957/4885SLC6A9 705/4885ALDH1A1 3873/4885
US-20040067924-A1 Actinium-225 complexes and conjugates for targeted radiotherapy CCR5, CXCR5, CXCR1 HSD17B10 2035/4885SLC6A9 2187/4885ALDH1A1 4269/4885
US-20030086868-A1 Actinium-225 complexes and conjugates for radioimmunotherapy H1-5, CHRND, H1-2 HSD17B10 3558/4885SLC6A9 3893/4885ALDH1A1 4111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.