Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
| ▸ | AHCY | P23526 | 2/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.40 |
| ▸ | AMD1 | P17707 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947531 | 0.90 | ADORA2A (0.48) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL18947542 | 0.88 | ADORA2A (0.36) | ADORA2AADORA2BAHCYAMD1ADORA3 | |
| SCHEMBL3662558 | 0.84 | ADORA3 (0.51) | ADORA2AADORA2BAHCYAMD1PI4KA | |
| SCHEMBL18947543 | 0.84 | ADORA2A (0.49) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL18947537 | 0.83 | AHCY (0.50) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL18947552 | 0.82 | ADORA2A (0.48) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL3654249 | 0.81 | CYP2C19 (0.41) | ADORA2AADORA2BADORA3ADORA1SLC29A1 | |
| SCHEMBL3660257 | 0.81 | PI4KA (0.40) | ADORA2AADORA2BAHCYAMD1PI4KA | |
| SCHEMBL18947533 | 0.78 | ADORA2A (0.36) | ADORA2AADORA2BAMD1PI4KAPI4K2B | |
| SCHEMBL18947545 | 0.78 | ADORA3 (0.36) | ADORA2AADORA2BDNMT1DNMT3BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676808-B2 | 2′,4′-substituted nucleosides as antiviral agents | GILEAD PHARMASSET LLC (US) | 2017-06-13 | — | — | US | disclosed |