Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.48 |
| ▸ | AHCY | P23526 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947540 | 0.88 | ADORA2A (0.35) | ADORA2AADORA2BAHCYPI4KAPI4K2B | |
| SCHEMBL18947543 | 0.86 | ADORA2A (0.49) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL18947537 | 0.85 | AHCY (0.50) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL15203798 | 0.83 | ADORA3 (0.54) | ADORA2AADORA2BAHCYPI4KAPI4K2B | |
| SCHEMBL18947534 | 0.82 | ADORA2A (0.48) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL18947531 | 0.82 | ADORA2A (0.48) | ADORA2AADORA2BAHCYDNMT1DNMT3B | |
| SCHEMBL12170655 | 0.80 | PI4KA (0.42) | ADORA2AADORA2BAHCYPI4KAPI4K2B | |
| SCHEMBL15203793 | 0.80 | PI4KA (0.42) | ADORA2AADORA2BAHCYPI4KAPI4K2B | |
| SCHEMBL15203741 | 0.79 | CYP2C19 (0.43) | ADORA2BAHCYADORA3ADORA1SLC29A1 | |
| SCHEMBL15203742 | 0.79 | CYP2C19 (0.43) | ADORA2BAHCYADORA3ADORA1SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676808-B2 | 2′,4′-substituted nucleosides as antiviral agents | GILEAD PHARMASSET LLC (US) | 2017-06-13 | — | — | US | disclosed |