Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995592 | 0.85 | LTA4H (0.48) | RAB9AHSD11B1HTTALDH1A1GAA | |
| SCHEMBL19571179 | 0.85 | LTA4H (0.48) | RAB9AHSD11B1HTTALDH1A1GAA | |
| SCHEMBL19737785 | 0.85 | RAB9A (0.52) | RAB9AHTTKDM4EALDH1A1TSHR | |
| SCHEMBL13995210 | 0.85 | LTA4H (0.48) | RAB9AHSD11B1HTTALDH1A1GAA | |
| SCHEMBL18948660 | 0.81 | RAB9A (0.55) | RAB9AHTTKDM4EALDH1A1TSHR | |
| SCHEMBL25728520 | 0.81 | RAB9A (0.48) | RAB9AHTTKDM4EALDH1A1TSHR | |
| SCHEMBL16681841 | 0.80 | ACE (0.49) | RAB9AHSD11B1KDM4ELTA4HNPSR1 | |
| SCHEMBL22021311 | 0.80 | ACE (0.49) | RAB9AHSD11B1KDM4ELTA4HNPSR1 | |
| SCHEMBL18735809 | 0.80 | ACE (0.49) | RAB9AHSD11B1KDM4ELTA4HNPSR1 | |
| SCHEMBL7309278 | 0.78 | ALDH1A1 (0.40) | RAB9AHSD11B1HTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |