Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917764 | 0.74 | ALDH1A1 (0.33) | — | |
| Bromide SCHEMBL7758524 | 0.66 | AKR1B1 (0.30) | — | |
| SCHEMBL30132988 | 0.62 | ALOX5 (0.51) | LMNA | |
| SCHEMBL30559940 | 0.60 | AKR1B1 (0.43) | — | |
| SCHEMBL21624172 | 0.60 | AKR1B1 (0.43) | — | |
| SCHEMBL3595402 | 0.60 | BRD4 (0.37) | LMNA | |
| SCHEMBL21624198 | 0.59 | ALOX5 (0.45) | — | |
| SCHEMBL30559951 | 0.59 | ALOX5 (0.45) | — | |
| SCHEMBL3595403 | 0.59 | BRD4 (0.36) | — | |
| SCHEMBL23590659 | 0.58 | BRD4 (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676703-B2 | Production method for 3,3-dimethyl-3,4-dihydro-1H-quinoxalin-2-one derivative and intermediate for said production method | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2017-06-13 | — | — | US | disclosed |