Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13268072 | 0.82 | SMN1; SMN2 (0.55) | LMNAHPGDSMN1; SMN2HTTHSD17B10 | |
| SCHEMBL20681766 | 0.81 | HPGD (0.46) | LMNAHPGDSMN1; SMN2HTTHSD17B10 | |
| SCHEMBL254148 | 0.81 | HSD17B10 (0.49) | LMNAHPGDSMN1; SMN2HTTHSD17B10 | |
| SCHEMBL19543517 | 0.81 | HSD17B10 (0.49) | LMNAHPGDSMN1; SMN2HTTHSD17B10 | |
| SCHEMBL16330014 | 0.81 | SMN1; SMN2 (0.54) | LMNAHPGDSMN1; SMN2HTTHSD17B10 | |
| SCHEMBL18557296 | 0.80 | LMNA (0.44) | LMNAHPGDSMN1; SMN2HTTHSD17B10 | |
| SCHEMBL18726810 | 0.80 | LMNA (0.44) | LMNAHPGDSMN1; SMN2HTTHSD17B10 | |
| SCHEMBL14934677 | 0.80 | HTT (0.52) | LMNAHPGDSMN1; SMN2HTTHSD17B10 | |
| SCHEMBL19401301 | 0.79 | HPGD (0.56) | HPGDSMN1; SMN2HTTHSD17B10TP53 | |
| SCHEMBL18557292 | 0.79 | LMNA (0.43) | LMNAHPGDSMN1; SMN2HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676864-B2 | Antibodies that specifically bind to the EphA2 receptor | SANOFI (FR) | 2017-06-13 | — | — | US | disclosed |