Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17740044 | 0.91 | LMNA (0.52) | HSD17B10PSMB5LMNAPKMNAMPT | |
| SCHEMBL12641968 | 0.91 | LMNA (0.43) | HSD17B10PSMB5LMNAPKMNAMPT | |
| SCHEMBL17175252 | 0.90 | NAMPT (0.43) | HSD17B10PSMB5LMNAPKMNAMPT | |
| SCHEMBL19116760 | 0.88 | PTGS1 (0.53) | LMNAPKMNAMPTHPGDALDH1A1 | |
| SCHEMBL14868081 | 0.88 | NAMPT (0.44) | HSD17B10PSMB5LMNAPKMNAMPT | |
| SCHEMBL19116362 | 0.88 | ALDH1A1 (0.43) | HSD17B10PSMB5LMNAPKMNAMPT | |
| SCHEMBL18553064 | 0.87 | HSD17B10 (0.39) | HSD17B10PSMB5LMNAPKMNAMPT | |
| SCHEMBL21727838 | 0.86 | PTGS1 (0.40) | HSD17B10PSMB5LMNAPKMHPGD | |
| SCHEMBL23395065 | 0.85 | PTGS1 (0.38) | HSD17B10PSMB5LMNAPKMNAMPT | |
| SCHEMBL21524521 | 0.85 | MGLL (0.44) | HSD17B10PSMB5LMNAPKMNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338578-A1 | MODIFIED VIRAL PARTICLES FOR GENE THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2023-10-26 | — | — | US | disclosed |
| US-11723990-B2 | Library of pH responsive polymers and nanoprobes thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-08-15 | — | — | US | disclosed |
| US-11723990-B2 | Library of pH responsive polymers and nanoprobes thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-08-15 | — | — | US | disclosed |
| US-11701433-B2 | Complexes for delivery of antigenic peptides | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-07-18 | — | — | US | disclosed |
| WO-2022101363-A1 | MODIFIED VIRAL PARTICLES FOR GENE THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2022-05-19 | — | — | WO | disclosed |
| US-20210338840-A1 | LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-11-04 | — | — | US | disclosed |
| US-11092594-B2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| WO-2021123116-A1 | ADHESIVE PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF | SKINOSIVE (FR) | 2021-06-24 | — | — | WO | disclosed |
| US-11013818-B2 | Library of pH responsive polymers and nanoprobes thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-05-25 | — | — | US | disclosed |
| EP-3443049-B1 | PHOTOACTIVE MACROMOLECULES AND USES THEREOF | BECKMAN COULTER INC (US) | 2021-04-14 | — | — | EP | disclosed |
| WO-2013152059-A1 | MULTICOLORED PH-ACTIVATABLE FLUORESCENCE NANOPLATFORM | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-10-10 | — | — | WO | disclosed |
| US-20120165393-A1 | Peptide-Based In Vivo siRNA Delivery System | Arrowhead Madison Inc. (US) | 2012-06-28 | — | — | US | disclosed |
| WO-2010129864-A9 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012017454-A1 | COUMARIN-CHALCONES AS ANTICANCER AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-02-09 | — | — | WO | disclosed |
| US-20100297725-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-20100284913-A1 | Methods and compositions for studying, imaging, and treating pain | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (US) | 2010-11-11 | — | — | US | disclosed |
| WO-2010129864-A2 | METHODS AND COMPOSITIONS FOR STUDYING, IMAGING, AND TREATING PAIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-11-11 | — | — | WO | disclosed |
| US-20100184087-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-07-22 | — | — | US | disclosed |
| US-20090181398-A1 | Nanoparticle conjugates | VENTANA MEDICAL SYSTEMS, INC. | 2009-07-16 | — | — | US | disclosed |
| WO-2009073546-A2 | MONOCLONAL ANTIBODY PARTNER MOLECULE CONJUGATES DIRECTED TO PROTEIN TYROSINE KINASE 7 (PTK7) | MEDAREX, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165393-A1 | Peptide-Based In Vivo siRNA Delivery System | VIP, RNASE1, APLNR | HSD17B10 4373/4885PSMB5 2563/4885LMNA 811/4885 |
| US-20210338840-A1 | LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF | MSN, CD44, CD47 | HSD17B10 2515/4885PSMB5 4797/4885LMNA 1128/4885 |
| US-11701433-B2 | Complexes for delivery of antigenic peptides | IFNG, ALB, IFNAR1 | HSD17B10 4675/4885PSMB5 365/4885LMNA 2853/4885 |
| US-20100297725-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | CRBN, GABBR1, SHBG | HSD17B10 2731/4885PSMB5 552/4885LMNA 3003/4885 |
| US-20230338578-A1 | MODIFIED VIRAL PARTICLES FOR GENE THERAPY | HAVCR2, TMEM205, COPA | HSD17B10 1711/4885PSMB5 796/4885LMNA 1297/4885 |
| US-20100284913-A1 | Methods and compositions for studying, imaging, and treating pain | INA, SCN3A, SCN9A | HSD17B10 4202/4885PSMB5 1504/4885LMNA 577/4885 |
| US-11723990-B2 | Library of pH responsive polymers and nanoprobes thereof | MSN, CD44, CD47 | HSD17B10 2515/4885PSMB5 4797/4885LMNA 1128/4885 |
| US-11092594-B2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | CRBN, AHR, RORB | HSD17B10 2140/4885PSMB5 682/4885LMNA 2273/4885 |
| US-11013818-B2 | Library of pH responsive polymers and nanoprobes thereof | MSN, CD44, CD47 | HSD17B10 2515/4885PSMB5 4797/4885LMNA 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.