SCHEMBL18950804

SCHEMBL18950804

CC(C)(C)OC(=O)Oc1c(C(C)(C)C)cc(NC(=O)O)cc1C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
VCAM1 P19320 13/20 0.40
ELANE P08246 1/20 0.37
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17171717 0.82 ALDH1A1 (0.44) ALDH1A1VCAM1ELANE
SCHEMBL17171796 0.80 ELANE (0.43) VCAM1ELANEPTGS2
SCHEMBL17546543 0.79 ELANE (0.50) VCAM1ELANE
SCHEMBL17546521 0.79 ELANE (0.42) VCAM1ELANE
SCHEMBL17546518 0.78 HSPA5 (0.42) VCAM1ELANE
SCHEMBL18950806 0.78 LMNA (0.41)
SCHEMBL17171752 0.78 ELANE (0.41) VCAM1ELANE
SCHEMBL17171733 0.77 VCAM1 (0.40) ALDH1A1GAATDP1VCAM1ELANE
SCHEMBL19293706 0.76 VCAM1 (0.41) VCAM1ELANE
SCHEMBL17171700 0.76 CA1 (0.50) VCAM1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178905-A1 ANTIOXIDANT FOR THERMOPLASTIC RESIN AND THERMOPLASTIC RESIN COMPOSITION INCLUDING SAME Adeka Corporation (JP) 2017-06-14 EP disclosed