SCHEMBL18952015

SCHEMBL18952015

c1cnc(-c2ccoc2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 14/20 0.50
CYP2D6 P10635 12/20 0.50
CYP3A4 P08684 12/20 0.50
MEN1 O00255 10/20 0.50
KMT2A Q03164 10/20 0.50
CYP2C19 P33261 10/20 0.50
HSD17B10 Q99714 10/20 0.50
ALDH1A1 P00352 8/20 0.50
USP2 O75604 8/20 0.50
MAPT P10636 7/20 0.50
ALOX15 P16050 6/20 0.50
KDM4E B2RXH2 3/20 0.50
TSHR P16473 3/20 0.50
TP53 P04637 1/20 0.50
CLK4 Q9HAZ1 5/20 0.47
LMNA P02545 4/20 0.47
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 5/20 0.45
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6847836 0.89 CLK4 (0.44) CYP1A2CYP2D6CYP3A4MEN1KMT2A
SCHEMBL29619599 0.79 CYP1A2 (0.42) CYP1A2CYP2D6CYP3A4MEN1KMT2A
SCHEMBL10142592 0.78 HTR7 (0.44) CYP1A2CYP2D6CYP3A4MEN1KMT2A
SCHEMBL21670474 0.77 CYP1A2 (0.42) CYP1A2CYP2D6CYP3A4MEN1KMT2A
SCHEMBL25733803 0.77 CYP1A2 (0.51) CYP1A2CYP2D6CYP3A4MEN1KMT2A
SCHEMBL16431002 0.77 CYP1A2 (0.51) CYP1A2CYP2D6CYP3A4MEN1KMT2A
SCHEMBL25719745 0.77 CYP1A2 (0.53) CYP1A2CYP2D6CYP3A4MEN1KMT2A
SCHEMBL28657158 0.76 NT5E (0.45) CYP1A2CYP2D6CYP3A4MEN1KMT2A
SCHEMBL2099096 0.76 KDM4E (0.52) CYP1A2CYP2D6CYP3A4MEN1KMT2A
Hydrochloric Acid SCHEMBL25229590 0.76 CYP1A2 (0.50) CYP1A2CYP2D6CYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022208382-A1 NOVEL DIALKOXYNAPHTHO[2,3-C]FURAN-1(3H)-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE OR SARS-COV-2 INFECTION DISEASE, COMPRISING SAME 동화약품주식회사 2022-10-06 WO claimed
CN-115181095-B Pyrimidine-based luminophore with fluorescence-delayed fluorescence-room temperature phosphorescence triple emission characteristics and preparation method thereof 天津大学 2024-03-22 CN disclosed
CN-112585184-B Method for reducing aldehyde emissions in polyurethane foams 陶氏环球技术有限责任公司 2023-04-11 CN disclosed
CN-115181095-A Pyrimidine-based luminophor with fluorescence-delayed fluorescence-room temperature phosphorescence triple emission characteristics and preparation method thereof 天津大学 2022-10-14 CN disclosed
WO-2022208382-A1 NOVEL DIALKOXYNAPHTHO[2,3-C]FURAN-1(3H)-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE OR SARS-COV-2 INFECTION DISEASE, COMPRISING SAME 동화약품주식회사 2022-10-06 WO disclosed
CN-114585618-A Fluorine-containing pyrimidine compound and method for producing same 优迈特株式会社 2022-06-03 CN disclosed
CN-114555566-A Organic compound and organic electroluminescent element comprising same 索路思高新材料有限公司 2022-05-27 CN disclosed
EP-3555095-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF Sunshine Lake Pharma Co., Ltd. (CN) 2019-10-23 EP disclosed
WO-2018157830-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-09-07 WO disclosed
EP-3362451-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF Sunshine Lake Pharma Co., Ltd. (CN) 2018-08-22 EP disclosed
WO-2018127096-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-07-12 WO disclosed
WO-2018108125-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-06-21 WO disclosed
WO-2017097234-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2017-06-15 WO disclosed