Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 13/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.42 |
| ▸ | USP2 | O75604 | 11/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 10/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25439871 | 0.89 | CYP1A2 (0.39) | CYP1A2CYP3A4USP2CYP2D6MEN1 | |
| SCHEMBL7191487 | 0.78 | LPL (0.46) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL18952015 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP3A4USP2CYP2D6MEN1 | |
| SCHEMBL29619599 | 0.75 | CYP1A2 (0.42) | CYP1A2CYP3A4USP2CYP2D6MEN1 | |
| SCHEMBL25440044 | 0.74 | ADORA2A (0.39) | CYP1A2CYP3A4USP2CYP2D6MEN1 | |
| SCHEMBL29620541 | 0.74 | CYP1A2 (0.58) | CYP1A2CYP3A4USP2CYP2D6MEN1 | |
| SCHEMBL1772039 | 0.73 | LPL (0.54) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C19 | |
| SCHEMBL28657158 | 0.72 | NT5E (0.45) | CYP1A2CYP3A4USP2CYP2D6MEN1 | |
| SCHEMBL3766081 | 0.71 | CYP1A2 (0.38) | CYP1A2CYP3A4USP2CYP2D6MEN1 | |
| SCHEMBL16431002 | 0.69 | CYP1A2 (0.51) | CYP1A2CYP3A4USP2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190293-A1 | RUBBER COMPOSITION, METHOD FOR MANUFACTURING RUBBER COMPOSITION, AND TIRE | BRIDGESTONE CORPORATION (JP) | 2020-06-18 | — | — | US | disclosed |
| EP-3608363-A1 | RUBBER COMPOSITION, METHOD FOR PRODUCING RUBBER COMPOSITION, AND TIRE | Bridgestone Corporation (JP) | 2020-02-12 | — | — | EP | disclosed |