Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535101 | 0.85 | RAPGEF4 (0.47) | LMNARAPGEF4ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL18952168 | 0.80 | CA1 (0.53) | LMNARAPGEF4KAT6AALDH1A1SMN1; SMN2 | |
| SCHEMBL15974991 | 0.74 | CA1 (0.59) | RAPGEF4ALDH1A1MAPTPOLBCA1 | |
| SCHEMBL28510674 | 0.70 | HTT (0.38) | LMNARAPGEF4ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4132176 | 0.69 | CNR2 (0.43) | RAPGEF4KAT6AMEN1KMT2ATP53 | |
| SCHEMBL25873556 | 0.69 | MEN1 (0.46) | NMT1LMNARAPGEF4ALDH1A1SMN1; SMN2 | |
| SCHEMBL14700843 | 0.69 | GRM4 (0.70) | — | |
| SCHEMBL11995566 | 0.68 | PTGS2 (0.46) | KAT6AALDH1A1L3MBTL1CA1CA2 | |
| SCHEMBL21875094 | 0.68 | HDAC1 (0.42) | KAT6ASMN1; SMN2L3MBTL1 | |
| SCHEMBL14529330 | 0.68 | CD44 (0.34) | LMNARAPGEF4MAPK10NPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362451-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017097234-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-06-15 | — | — | WO | disclosed |