Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18952140 | 0.85 | NMT1 (0.36) | RAPGEF4LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL29065515 | 0.81 | RAPGEF4 (0.47) | RAPGEF4LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL20535401 | 0.78 | RAPGEF4 (0.44) | RAPGEF4LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL15974991 | 0.77 | CA1 (0.59) | RAPGEF4GAAALDH1A1MAPTPOLB | |
| SCHEMBL28726287 | 0.74 | ALDH1A1 (0.42) | RAPGEF4LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL20534977 | 0.73 | RAPGEF4 (0.48) | RAPGEF4LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL14529330 | 0.73 | CD44 (0.34) | RAPGEF4LMNAGAA | |
| SCHEMBL18952089 | 0.73 | RAPGEF4 (0.48) | RAPGEF4LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28510674 | 0.72 | HTT (0.38) | RAPGEF4LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL6581959 | 0.69 | SMN1; SMN2 (0.79) | LMNASMN1; SMN2GAAALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114366748-A | Crystalline solid forms of BET inhibitors | 因赛特公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-109715625-B | Crystalline solid forms of BET inhibitors | 因赛特公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114369091-A | Crystalline solid forms of BET inhibitors | 因赛特公司 | 2022-04-19 | — | — | CN | disclosed |
| EP-3609896-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018188047-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2018-10-18 | — | — | WO | disclosed |