Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18952517 | 0.82 | CTSS (0.30) | — | |
| SCHEMBL3563505 | 0.73 | MIF (0.43) | DPP4PLAUPLAUR | |
| SCHEMBL18952358 | 0.68 | ACACB (0.30) | — | |
| SCHEMBL2472950 | 0.68 | EPHX1 (0.36) | ALDH1A1PLAUPLAUR | |
| SCHEMBL2466830 | 0.68 | EPHX1 (0.55) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4888830 | 0.67 | EPHX1 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5073587 | 0.67 | MIF (0.39) | RAB9AMEN1KMT2A | |
| SCHEMBL2344981 | 0.66 | SMN1; SMN2 (0.42) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6865246 | 0.66 | NPC1 (0.31) | RAB9A | |
| SCHEMBL15547346 | 0.66 | MTNR1A (0.43) | ALDH1A1RAB9ALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386951-A1 | PHENYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS | H. Hoffnabb-La Roche Ag (CH) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017097732-A1 | PHENYL DERIVATIVES AS CANNABINOID RECEPTOR 2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-15 | — | — | WO | disclosed |