Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | EIF4E | P06730 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753663 | 0.78 | HDAC3 (0.35) | EIF4EALDH1A1KMT2A | |
| SCHEMBL208797 | 0.77 | GFER (0.42) | ALDH1A1KMT2ANOTUM | |
| SCHEMBL2750624 | 0.76 | RAB9A (0.38) | ALDH1A1KMT2ANOTUM | |
| SCHEMBL8649872 | 0.75 | EPHB4 (0.40) | BCHE | |
| SCHEMBL18952631 | 0.75 | CYP1A1 (0.39) | APEX1BCHEHSD11B1 | |
| SCHEMBL694300 | 0.74 | RAB9A (0.47) | HSD11B1ALDH1A1KMT2AAHR | |
| SCHEMBL18952679 | 0.73 | EIF4E (0.40) | APEX1BCHEEIF4EDHODHAR | |
| SCHEMBL2894960 | 0.72 | HSD11B1 (0.39) | PDK2HSD11B1 | |
| SCHEMBL2752772 | 0.71 | ALDH1A1 (0.40) | EIF4EALDH1A1 | |
| SCHEMBL14562911 | 0.71 | NPC1 (0.39) | ALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386973-A1 | PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017097927-A1 | PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-15 | — | — | WO | disclosed |