SCHEMBL1895295

SCHEMBL1895295

CC(C)C(C(=O)O)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 2/20 0.47
CYP2D6 P10635 1/20 0.43
ACP3 P15309 1/20 0.43
AOC3 Q16853 1/20 0.42
ADRB2 P07550 1/20 0.42
ADRB1 P08588 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CASP1 P29466 1/20 0.40
IGFBP3 P17936 1/20 0.38
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
IDO2 Q6ZQW0 1/20 0.38
HDAC1 Q13547 1/20 0.38
OPRM1 P35372 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30180175 1.00 CXCL8 (0.47) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL30370722 0.87 CXCL8 (0.46) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL23886481 0.87 CXCL8 (0.46) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL23886958 0.87 CXCL8 (0.46) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL23886598 0.87 CXCL8 (0.46) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL23886478 0.87 CXCL8 (0.46) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL23886475 0.87 CXCL8 (0.46) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL1669592 0.85 CYP1A2 (0.47) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL27469439 0.85 ADRB2 (0.42) CXCL8CYP2D6ACP3AOC3ADRB2
SCHEMBL4659044 0.80 CXCL8 (0.63) CXCL8ACP3ADRB2ADRB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5786428-A POLYMER MATRIX OF UNSATURATED MONOMER AND METAL COMPLEX HAVING A LIGAND AND A POLYMERIZABLE UNSATURATED MOIETY; EFFICIENT, RAPID AND SIMPLE PURIFICATION; MEDICAL DIAGNOSIS; CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-07-28 US claimed
EP-0114012-B1 ESTERS OF CYCLOPROPANE-CARBOXYLIC ACIDS AND UNSATURATED ALIPHATIC ALCOHOLS, PROCESS AND INTERMEDIATES OF PREPARATION AND PESTICIDAL COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1986-10-08 EP claimed
US-20230172981-A1 METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) 2023-06-08 US disclosed
EP-3925437-A1 PLANT GROWING SYSTEM OMS Investments, Inc. (US) 2021-12-22 EP disclosed
US-11154015-B2 Plant growing system and methods of using the same OMS INVESTMENTS, INC. (US) 2021-10-26 US disclosed
US-20210317407-A1 METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS Seattle Children's Hospital (dba Seattle Children's Research Institute) 2021-10-14 US disclosed
EP-2814315-B1 PLANT GROWING SYSTEM AND METHODS OF USING THE SAME OMS INVEST INC (US) 2021-07-28 EP disclosed
US-20200288643-A1 PLANT GROWING SYSTEM AND METHODS OF USING THE SAME JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2020-09-17 US disclosed
US-10602673-B2 Plant growing system and methods of using the same OMS INVESTMENTS, INC. (US) 2020-03-31 US disclosed
US-20150156973-A1 PLANT GROWING SYSTEM AND METHODS OF USING THE SAME OMS INVESTMENTS, INC. (US) 2015-06-11 US disclosed
US-9012363-B2 Granular controlled release agrochemical compositions and process for the preparation thereof EVERRIS INTERNATIONAL B.V. (NL) 2015-04-21 US disclosed
US-20070072775-A1 Granular controlled release agrochemical compositions and process for the preparation thereof OMS INVESTMENTS, INC. (US) 2007-03-29 US disclosed
US-5786428-A POLYMER MATRIX OF UNSATURATED MONOMER AND METAL COMPLEX HAVING A LIGAND AND A POLYMERIZABLE UNSATURATED MOIETY; EFFICIENT, RAPID AND SIMPLE PURIFICATION; MEDICAL DIAGNOSIS; CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-07-28 US disclosed
US-5089511-A Trifluoromethylvinyl compounds ROUSSEL UCLAF (FR) 1992-02-18 US disclosed
US-4920231-A Reacting with trifluoroacetic acid with halovinyl compound in presence of cuprous salt ROUSSEL UCLAF (FR) 1990-04-24 US disclosed
EP-0274546-A1 New oxazolinone compounds useful as intermediates for the preparation of insecticidal and acaracidal cinnamide compounds AMERICAN CYANAMID COMPANY (US) 1988-07-20 EP disclosed
EP-0223521-A2 Insecticidal and acaricidal phenoxypyridinyl esters and intermediates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-05-27 EP disclosed
US-4390543-A Substituted pyridine methyl esters of 2-isopropyl-2-(4-chlorophenyl) acetic acid and their use as insecticides MALHOTRA SUDARSHAN K 1983-06-28 US disclosed
US-4262001-A MITICIDES, PARASITICIDES, LARVICIDES THE DOW CHEMICAL COMPANY (US) 1981-04-14 US disclosed
US-4228172-A Substituted pyridine methyl esters of 2-isopropyl-2-(4-chlorophenyl)acetic acid and their use as insecticides THE DOW CHEMICAL COMPANY (US) 1980-10-14 US disclosed