Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663906 | 1.00 | CXCL8 (0.63) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL29718684 | 1.00 | CXCL8 (0.63) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL5672222 | 1.00 | CXCL8 (0.63) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL15695552 | 0.88 | CXCL8 (0.50) | CXCL8ACP3GLSADRB2ADRB1 | |
| SCHEMBL16798960 | 0.88 | CXCL8 (0.50) | CXCL8ACP3GLSADRB2ADRB1 | |
| SCHEMBL16023820 | 0.88 | CXCL8 (0.50) | CXCL8ACP3GLSADRB2ADRB1 | |
| SCHEMBL27603271 | 0.85 | CXCL8 (0.47) | CXCL8ACP3GLSADRB2ADRB1 | |
| SCHEMBL2204495 | 0.84 | PTGS2 (0.56) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL15568192 | 0.84 | CXCL8 (0.59) | CXCL8PTGS2MMP1MMP2MMP9 | |
| SCHEMBL15568736 | 0.84 | CXCL8 (0.59) | CXCL8PTGS2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835688-A | Substituted 4-aryl imidazole-2-ketone derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| EP-2004789-A1 | A STABILIZED LIQUID ENZYME COMPOSITION | Novozymes A/S (DK) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007113241-A1 | A STABILIZED LIQUID ENZYME COMPOSITION | NOVOZYMES A/S (DK) | 2007-10-11 | — | — | WO | disclosed |
| WO-1996002492-A1 | METHOD OF MAKING A BENZYLPROPANAMINE | NSP PHARMACEUTICALS, INC. (US) | 1996-02-01 | — | — | WO | disclosed |