Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979015 | 0.89 | AR (0.45) | MMP13XDHPTGDRAR | |
| SCHEMBL15536746 | 0.86 | MMP13 (0.41) | MMP13AR | |
| SCHEMBL15535817 | 0.86 | MMP13 (0.41) | MMP13AR | |
| SCHEMBL18952942 | 0.84 | GPR119 (0.40) | MMP13XDH | |
| SCHEMBL18952955 | 0.84 | MMP13 (0.42) | MMP13AR | |
| SCHEMBL18952979 | 0.83 | MMP13 (0.41) | MMP13AR | |
| SCHEMBL18952954 | 0.82 | MMP13 (0.42) | MMP13AR | |
| SCHEMBL13832579 | 0.81 | AR (0.36) | MMP13XDHPTGDRARGCK | |
| SCHEMBL1979251 | 0.80 | AR (0.35) | MMP13XDHPTGDRAR | |
| SCHEMBL18952980 | 0.79 | PTGDR (0.34) | XDHPTGDRARGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386506-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | Autifony Therapeutics Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098254-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |