Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18952940 | 0.87 | GPR119 (0.39) | XDHARHRH3 | |
| SCHEMBL15536428 | 0.87 | CHRM2 (0.34) | ARHRH3 | |
| SCHEMBL19670125 | 0.83 | PTGDR (0.37) | PTGDRIRAK4XDHARHRH3 | |
| SCHEMBL1980154 | 0.81 | IRAK4 (0.36) | PTGDRIRAK4XDHARGCK | |
| SCHEMBL18952992 | 0.79 | MMP13 (0.39) | PTGDRXDHARGCK | |
| SCHEMBL1979251 | 0.78 | AR (0.35) | PTGDRIRAK4XDHAR | |
| SCHEMBL1979015 | 0.78 | AR (0.45) | PTGDRXDHAR | |
| SCHEMBL13832579 | 0.76 | AR (0.36) | PTGDRIRAK4XDHARGCK | |
| SCHEMBL15536372 | 0.75 | OXTR (0.36) | ARHRH3 | |
| SCHEMBL23957604 | 0.75 | PTGDR (0.34) | PTGDRIRAK4XDHARHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386506-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | Autifony Therapeutics Limited (GB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098254-A1 | MODULATORS OF KV3 CHANNELS TO TREAT PAIN | AUTIFONY THERAPEUTICS LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |