Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954706 | 0.83 | ALDH1A1 (0.43) | ALDH1A1AGTR1HSD17B10CUL4AMAPT | |
| SCHEMBL18954838 | 0.80 | CUL4A (0.40) | ALDH1A1CUL4APARK7 | |
| SCHEMBL18954744 | 0.76 | ALDH1A1 (0.74) | ALDH1A1AGTR1HSD17B10MAPTHTT | |
| SCHEMBL18954631 | 0.76 | PARK7 (0.58) | ALDH1A1HSD17B10LMNAMAPTTP53 | |
| SCHEMBL18954597 | 0.75 | ALDH1A1 (0.62) | ALDH1A1AGTR1HSD17B10NPC1LMNA | |
| SCHEMBL18955251 | 0.75 | ALDH1A1 (0.75) | ALDH1A1AGTR1HSD17B10CUL4AMAPT | |
| SCHEMBL18954712 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HSD17B10LMNAMAPTHTT | |
| SCHEMBL18974291 | 0.74 | ALDH1A1 (1.00) | ALDH1A1AGTR1HSD17B10POLBMAPT | |
| SCHEMBL18954703 | 0.73 | ALDH1A1 (0.72) | ALDH1A1AGTR1HSD17B10CUL4ANPC1 | |
| SCHEMBL18955380 | 0.73 | ALDH1A1 (0.67) | ALDH1A1AGTR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |