Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.37 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14884754 | 0.88 | CUL4A (0.47) | CUL4ACA12CA9ALDH1A1ALDH2 | |
| SCHEMBL18954505 | 0.80 | ALDH1A1 (0.61) | CUL4AALDH1A1PARK7 | |
| SCHEMBL18954706 | 0.80 | ALDH1A1 (0.43) | CUL4AALDH1A1PARK7 | |
| SCHEMBL18954631 | 0.80 | PARK7 (0.58) | CA12CA9ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL28527361 | 0.79 | CES1 (0.43) | CA12CA9ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18954678 | 0.77 | CASP3 (0.45) | CA12CA9ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18954709 | 0.76 | CHRM5 (0.48) | CA12CA9ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL14884742 | 0.76 | PARK7 (0.65) | CUL4ACA12CA9ALDH1A1ALDH3A1 | |
| SCHEMBL14876475 | 0.76 | PARK7 (0.49) | CUL4ACA12CA9ALDH1A1ALDH3A1 | |
| SCHEMBL3010838 | 0.76 | ALDH3A1 (0.64) | CUL4ACA12CA9ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |