Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954597 | 0.89 | ALDH1A1 (0.62) | ALDH1A1HSD17B10AGTR1MAPTHTT | |
| SCHEMBL18955059 | 0.85 | ALDH1A1 (0.70) | ALDH1A1HSD17B10MAPTHTTPOLB | |
| SCHEMBL18954534 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10AGTR1MAPTHTT | |
| SCHEMBL18954744 | 0.80 | ALDH1A1 (0.74) | ALDH1A1HSD17B10AGTR1MAPTHTT | |
| SCHEMBL18954539 | 0.76 | ALDH1A1 (0.62) | ALDH1A1HSD17B10AGTR1MAPTHTT | |
| SCHEMBL18954588 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10MAPTHTTPOLB | |
| SCHEMBL18955406 | 0.73 | ALDH1A1 (0.73) | ALDH1A1HSD17B10AGTR1MAPTHTT | |
| SCHEMBL18954553 | 0.73 | MAPT (0.45) | ALDH1A1HSD17B10MAPTHTTPOLB | |
| SCHEMBL18974291 | 0.72 | ALDH1A1 (1.00) | ALDH1A1HSD17B10AGTR1MAPTPOLB | |
| SCHEMBL18954457 | 0.72 | MAPT (0.43) | ALDH1A1HSD17B10MAPTHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |