Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16047437 | 0.86 | ALDH1A1 (0.49) | L3MBTL1ALDH1A1CES1 | |
| SCHEMBL11147987 | 0.85 | ALDH1A1 (0.47) | MAPTTP53L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18954588 | 0.81 | ALDH1A1 (0.53) | MAPTTP53L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18954457 | 0.80 | MAPT (0.43) | MAPTTP53L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18955059 | 0.77 | ALDH1A1 (0.70) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL9095600 | 0.75 | DRD2 (0.57) | ALDH1A1 | |
| SCHEMBL4597472 | 0.74 | ALDH1A1 (0.50) | MAPTTP53L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL16048101 | 0.73 | ALDH3A1 (0.65) | ALDH1A1 | |
| SCHEMBL18954789 | 0.73 | ALDH1A1 (0.71) | MAPTTP53L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL18954534 | 0.73 | ALDH1A1 (0.50) | MAPTTP53L3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |